Ansasteroide: Neues von einem neuartigen Verbindungstyp

Abstract

In this report we communicate recent results from our investigations with ansa-steroids. Following a detailed inspection of the stereoselectivity of epoxidations, a highly regioselective Baeyer-Villiger oxidation to form lactones was developed. After deciding on the proper starting material, we were also quite successful with the Birch reduction of the aromatic ring to generate cyclohexadienes. Efforts to open the five-membered ring via autoxidation and fragmentation met with failure.