(Trimethylsilyl)alanine: a Metabolically Stable 'Bio-Isostere' for Phenylalanine
DOI:
https://doi.org/10.2533/chimia.1992.312Abstract
The preparation of protected derivatives of enantiomerically pure β-(trimethylsilyl)alanine (1) and their chemical properties are decribed. Examples of renin inhibitory peptides, containing 1 are given, which demonstrates its use as a 'bio-isosteric' replacement for phenylalanine (2).
Downloads
Published
1992-08-19
Issue
Section
Forschung
License
Copyright (c) 1992 Swiss Chemical Society
![Creative Commons License](http://i.creativecommons.org/l/by-nc/4.0/88x31.png)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
[1]
B. Weidmann, Chimia 1992, 46, 312, DOI: 10.2533/chimia.1992.312.