Détermination de la composition d'une préparation médicinale frauduleuse par des méthodes chromatographiques couplées (GC/MS, GC-FTIR, HPLC-DAD). Le cas des pilules chinoises Chuifong-Touku wan

Abstract

The hyphenated techniques in chromatography (GC/MS, GC-FTIR, HPLC-DAD) are available for the molecular analysis of organic compounds. A traditional herbal medicine claimed to have a natural composition is studied by these appropriate methods. The analysis of crude and derivatized extracts of the pills showed that they are constitued by a mixture of synthetic drugs (mefenamic acid, indomethacine, hydrochlorothiazid, and diazepam) and some herbal compounds.