Bildung 12- bis 40-gliedriger Oligolide aus enantiomerenreinen 3-Hydroxybuttersäure-Derivaten – Bausteine für eine 2₁- und eine 3₁-Helix
DOI:
https://doi.org/10.2533/chimia.1991.376Abstract
Trimeric, tetrameric, and pentameric oligolides are formed preferentially from (S)-βbutyrolactone, or from methyl (R)-3-hydroxybutanoate, upon prolonged treatment with catalytic amounts of tetraoxadistannacyclodecane (Shanzer's macrolactonization catalyst) in refluxing xylene. The crystal structure of the tetramer is described. Substructures of the larger folded oligolides are used for the construction of a left-handed 21-helix, as found in the biopolymer PHB, and a heretofore unknown right-handed 31-helix.
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1991-12-18
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Forschung
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Copyright (c) 1991 Swiss Chemical Society
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
[1]
Chimia 1991, 45, 376, DOI: 10.2533/chimia.1991.376.