LC for Sample Preparation in Coupled LC-GC: A Review

Authors

  • Konrad Grob

DOI:

https://doi.org/10.2533/chimia.1991.109

Abstract

In chromatographic trace analysis, most of the working time is spent in preparing the sample; the methods involved are largely inefficient, often rather primitive. (HP)LC could replace a good part of this pre-separation, clean-up or sample enrichment work. It offers high separation efficiency, a wide range of selectivities, and accurate control through on-line detection. LC work is reviewed that is related to on-line LC-GC, showing the wealth of possibilities available for LC sample preparation. The present problems are discussed, hoping to motivate colleagues getting involved in the development of advanced sample preparation techniques.

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Published

1991-04-24

Issue

Section

Forschung