Ketoins from Primary Alkylhalides, Grignard Compounds and Carbonmonoxide in Ether-HMPT

Authors

  • W.J.J.M. Sprangers Department of Organic Chemistry, Gorlaeus Laboratories, The University of Leiden
  • A.P. van Swieten Department of Organic Chemistry, Gorlaeus Laboratories, The University of Leiden
  • R. Louw Department of Organic Chemistry, Gorlaeus Laboratories, The University of Leiden

DOI:

https://doi.org/10.2533/chimia.1976.199

Abstract

Whereas carbonylation of primary Grignard compounds in ether-HMPT leads to ketones 1, reaction in the presence of an additional amount of alkylhalide results in the formation of hydroxyketones 2 and 3. When using neat HMPT as solvent, 2 is the main product (up to 55 % yield).

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Published

1976-03-31

Issue

Vol. 30 No. 3 (1976): Forschung/Research

Section

Kurze Mitteilungen

License

Copyright (c) 1976 W.J.J.M. Sprangers

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

[1]
W. Sprangers, A. van Swieten, R. Louw, Chimia 1976, 30, 199, DOI: 10.2533/chimia.1976.199.